Title: An open-label, randomized, crossover study to evaluate the bioavailability of nanoemulsion versu conventional fat-soluble formulation of cholecalciferol in healthy participants
Authors: Raman Kumar Marwaha, Manish Verma, Ajit Walekar, Rakesh Sonawanc, Chirag Trivedi
Published: Journal of Clinical Orthopedics and Trauma. 2019;10: 1094-1096
Title: Interventions for prevention and control of epidemic of Vitamin D deficiency
Authors: R.K. Marwaha & Dr. Aashima Dabas
Published: The Indian Journal of Pediatrics, 2019; 86: 532-537.
Title: Impact of Solar UVB radiation (290-320) on vitamin D synthesis in children with type IV and V skin
Authors: R. K. Marwaha, V. Sreenivas, D. Talwar, V.K. Yenamandra, A. Challac, R. Lakshmy, V.K. Sharma, G. Sethuraman
Published: British Journal of Dermatology, 2015 173(2):604-6
Conclusion: The ultraviolet B rays of wavelength 290-320 nano meters responsible for synthesis of vitamin D in the skin is highest between 11am to 1pm. No increase in the serum vitamin D was observed following sun exposure in winter emphasising the need for vitamin D supplementation during winter months.
Title: Regional and seasonal variations in Ultraviolet B irradiation and vitamin D synthesis in India
Authors: R.K. Marwaha and V.K. Yenamandra
Published: Osteoporosis Int. 2016 27: 1611-17
Title: Efficacy of micellized vs fat-soluble vitamin D3 supplementation in healthy school children from Northern India.
Authors: R.K. Marwaha, V.K. Yenamandra, M.A. Ganie, G. Sethuraman , V. Sreenivas, L. Ramakrishnan, S.K. Mathur and A. Mithal
Published: JPEM ; 2016:12: 1373-1377
Conclusion: Both fat soluble and Nano Vitamin D supplementation increase the serum 25(OH)D levels but Nano form of vitamin D3 appears to be far more efficacious in achieving higher levels of serum 25(OH)D (vitamin D) than that observed with a similar dose of fat-soluble vitamin D3.
Title: Assessment of insulin like growth factor-1 and IGF binding protein in healthy Indian girls from Delhi and their correlation with age, pubertal status, obesity and thyroid hormonal status
Authors: R.K. Marwaha
Published: JPEM ; 2017. 30; 739-747
Conclusion: This study for the first-time established age wise levels of insulin growth factors (IGF-1) and insulin growth factors binding proteins (IGFBP-3) which are important for the management of children with short stature. No significant impact of age on IGF-1 and IGFBP-3 was observed in pre-pubertal girls. A sudden marked increase at 11 years followed by a gradual rise in growth factors till 16 years was indicative of pubertal initiation and maturation. Subclinical hypothyroidism did not influence growth factors in girls.
Title: Reference range of random urinary calcium creatine ratio in North Indian children and adolescents. Annals of Pediatric Endocrinology and Metabolism
Authors: R.K. Marwaha
Published: APEM.2019; 24: 1-7
Conclusion: Urinary calcium creatinine ratio (UCaCrR) is a reliable indicator for monitoring hypercalciuria following vitamin D supplementation. Our study established UCaCrR of 0.13 as the cutoff value for hypercalciuria in North Indian children and adolescents with adequate dietary intake of calcium and sufficient serum vitamin D levels.
Title: A randomised controlled trial comparing the efficacy of micellised and fat-soluble vitamin D3 supplementation in healthy adults.
Authors: R.K. Marwaha
Published: Br J Nutr. 2019; 121:859-865.
Conclusion: This randomized control trial confirmed the findings of our earlier pilot study that Nano/Miscellised vitamin D is superior to conventional fat-soluble vitamin D in achieving higher levels of vitamin D in the blood.
Title: Efficacy of daily supplementation of milk fortified with Vitamin D2 for three months in healthy school children: A randomised placebo controlled trial
Authors: Marwaha R.K., Dabas A, Puri S, Kalaivani M, Dabas V, Yadav S, Darg A, Pullakhandam R, Gupta S and Narang A
Published: Indian Pediatrics 2021;58:820-825
Conclusion: Supplementation of milk fortified with approximately 240 IU Vitamin D2 for three months did not achieve sufficient serum 25(OH)D levels in Indian children with vitamin D deficiency during winter.
Title: Daily vs weekly oral Vitamin D3 therapy fr nutritional rickets in Indian children: A randomised controlled open-label trial
Authors : Dabas A, Dabas V, Dabla PK, Marwaha R K, Yadav S, Bhardavaj M, Tyagi V and Agrawal S.
Published: Br J Nutr. 2022 13;1-8, doi: 10.1017?S0007114522001477.
Conclusion: In view of limited trials in children which have compared the efficacy of daily or weekly low-dose vitamin D regime in rickets, we undertook this study to evaluate the efficacy of daily with weekly oral vitamin D3 therapy in radiological healing of nutritional rickets.
Title: Normative data for insulin-like growth factor IGF-1 in healthy children and adolescents from India.
Authors : Teja KVR, Malhotra B, Vogel M, Marwaha RK, Aggarwal A, Pal R, Das L, Sachdeva N, Devi N, Bansal D, Rastogi A, Sharma S, Devvan G, Bhadada SK, Ghosh J, Monoghan PJ. Korbonits M, Dutta P
Published: 'Journal of Clinical Endocrinology and Metabolism' 2024 May 15 : dgae340.doi: 10.1210/clinem/dgae340.
Effects of Vitamin D Supplementation as add- on therapy on the immune repertoire in recipients of the ChAdOx1 nCoV-19 Vaccine: A prospective randomised placebo controlled trial
A collaborative project between SEHEAC and Boston Medical School, USA.
Article 1: Effect of calcifediol supplementation as add-on therapy on the immune repertoire in recipients of the ChAdOx1 nCov-19 vaccine:A placebo-controlled, clinical trial
Authors: Swati Bhat, Liza Das , Deep Maheshwari, Darshan Badal, Roman Sarkar, Madhu Gupta , Surinder Singh Pandav, Bijaya Kumar Padhi, Sanjay Kumar Bhadada, Michael F. Holick, Pinaki Dutta, Naresh Sachdeva , Raman Kumar Marwaha.
Published : ‘Journal of Infection’ as Letter to the Editor with an impact factor of 38. This is one of highest rated journals.
j.Intect 2023 May;86(5):e120-e122
Article 2: Calcifediol boosts efficacy of ChAdOx1 nCoV-19 vaccine by upregulating genes promoting memory T cell responses
Authors: Himanshu Singh Saroha, Swati Bhat, Liza Das, Pinaki Dutta 1, Michael F Holick, Naresh Sachdeva, Raman Kumar Marwaha
Published : NPJ Vaccines/2024(9):114
Article 3: Impact of BMI on serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D with calcifediol supplementation in young adults: a longitudinal study
Authors: Liza Das, Naresh Sachdeva, Michael F Holick, Mahesh Devnani, Pinaki Dutta, Raman Kumar Marwaha
Published : Endocrine.2024 86(1):391-399